منابع مشابه
Axo-Glial Septate Junctions
The L 1 subgroup of the immunoglobulin G superfamily participates in neurite outgrowth, neurite fasciculation and inter-neuronal adhesion. Almost all functional studies of the L 1 family have focused on their role in neurons. In this issue of the Journal of Cell Biology (Tait et al., 2000), the 155kD isoform of neurofascin, an ankyrin binding member of the L 1 family is identified as the first ...
متن کاملAxo-axonic Septate Junctions in the Basket Formations of the Cat Cerebellar Cortex
In the cat cerebellar cortex, as in most higher vertebrates, the descending branches of the basket cell axon envelop the Purkinje cell body in the region of its axon hillock in a basket-like arborization (Rambn y Cajal, 1909) . This report further characterizes the basket formations of the cat and describes septate junctions between the descending branches of the basket cell axons and between s...
متن کاملAxo-Glial Interactions Regulate the Localization of Axonal Paranodal Proteins
Mice incapable of synthesizing the abundant galactolipids of myelin exhibit disrupted paranodal axo-glial interactions in the central and peripheral nervous systems. Using these mutants, we have analyzed the role that axo-glial interactions play in the establishment of axonal protein distribution in the region of the node of Ranvier. Whereas the clustering of the nodal proteins, sodium channels...
متن کاملElectron tomography of paranodal septate-like junctions and the associated axonal and glial cytoskeletons in the central nervous system.
The polarized domains of myelinated axons are specifically organized to maximize the efficiency of saltatory conduction. The paranodal region is directly adjacent to the node of Ranvier and contains specialized septate-like junctions that provide adhesion between axons and glial cells and that constitute a lateral diffusion barrier for nodal components. To complement and extend earlier studies ...
متن کاملSeptate and Gap Junctions in Molluscan Gill Epithelium
Previous studies on the electrically-coupled gill epithelium of the mussel Elliptio complanatus failed to reveal the presence of gap junctions . Therefore, the septate junction, which is present as a prominent belt between all the epithelial cells in this tissue, seemed to be an attractive candidate for providing the low-resistance pathway necessary for electrical coupling (7, 19), as also was ...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2000
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.150.3.f97